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Current publications

2020

Schäfer K.-H., Christmann A., Gries M. Can we trust the gut? The role of the intenstine in neurodegeneration. The Journal of Physiology. 2020 July 24. dx.doi.org/10.1113/JP280336.

 

Manuela Gries, Anne Christmann, Steven Schulte, Maximilian Weyland, Stephanie Rommel, Monika Martin, Marko Baller, Ralph Röth, Stefanie Schmitteckert, Marcus Unger, Yang Liu, Frederik Sommer, Timo Mühlhaus, Michael Schroda, Jean-Pierre Timmermans, Isabel Pintelon, Gudrun Rappold, Markus Britschgi, Hilal Lashuel, Michael D. Menger, Matthias W. Laschke, Beate Niesler, Karl-Herbert Schäfer. Functional and molecular early enteric biomarkers for Parkinson’s disease in mice and men. prepublished in bioarxive doi: doi.org/10.1101/2020.06.06.136556

 

Nguyen V. T. T. & Endres K. A crate of Pandora: do amyloids from bacteria promote Alzheimer’s disease? Neural Reg Res 2020

 

Schnöder L, Gasparoni G, Nordström K, Schottek A, Tomic I, Christmann A, Schäfer KH, Menger MD, Walter J, Fassbender K, Liu Y. Neuronal deficiency of p38α-MAPK ameliorates symptoms and pathology of APP or Tau-transgenic Alzheimer's mouse models. FASEB J. 2020 May 31. doi: 10.1096/fj.201902731RR. Online ahead of print.PMID: 32475008

 

dos Santos Guilherme M., Todorov H., Osterhof C., Möllerke A. , Cub K., Hankeln T., Gerber S. and Endres K. Impact of cute and Chronic Amyloid-β Peptide Exposure on Gut Microbial Commensals in the Mouse. Front. Microbiol., 20 May 2020 doi.org/10.3389/fmicb.2020.01008.

 

Delport A, Kins S, Hewer R. The amyloid precursor protein affects glyceraldehyde 3-phosphate dehydrogenase levels, organelle localisation and thermal stability. Mol Biol Rep. 2020 Apr;47(4):3019-3024. doi: 10.1007/s11033-020-05364-z. Epub 2020 Mar 9. PMID: 32152789.

 

Eggert S, Gruebl T, Rajender R, Rupp C, Sander B, Heesch A, Zimmermann M, Hoepfner S, Zentgraf H, Kins S. The Rab5 activator RME-6 is required for amyloid precursor protein endocytosis depending on the YTSI motif. Cell Mol Life Sci. 2020 Feb 17. doi: 10.1007/s00018-020-03467-1. Epub ahead of print. PMID: 32065241.

 

Endres K. Amyloidogenic Peptides in Human Neuro-Degenerative Diseases and in Microorganisms: A Sorrow Shared Is a Sorrow Halved? Molecules 2020, 25, 925; doi:10.3390/molecules25040925

 

Gadomsky L, Santos Guilherme MD, Winkler J, der Kooij MV, Hartmann T, Grimm M, Endres K. Elevated Testosterone Level and Urine Scent Marking in Male 5xFAD Alzheimer Model Mice. Curr Alzheimer Res. 2020 Feb 16. doi: 10.2174/1567205017666200217105537.

 

Kiss E, Groeneweg F, Gorgas K, Schlicksupp A, Kins S, Kirsch J, Kuhse J. Amyloid-β Fosters p35/CDK5 Signaling Contributing to Changes of Inhibitory Synapses in Early Stages of Cerebral Amyloidosis. J Alzheimers Dis. 2020;74(4):1167-1187. doi: 10.3233/JAD-190976. PMID: 32144981.

 

Stoye N.M., dos Santos Guilherme M., Endres K. Alzheimer’s disease in the gut – major changes in the gut of 5xFAD model mice with ApoA1 as potential key player. FASEB J 2020 (angenommenes Manuskript).

 

Wagener K., Bros M., Krumb M., Langhanki J., Pektor S., Worm M., Schinnerer M., Montermann E., Miederer M., Frey H., Opatz T., Rösch F. (2020) Targeting of Immune Cells with Trimannosylated Liposomes, Advanced Therapeutics, 1900185.

 

F. Daus, E. Pfeifer, K. Seipp, N. A. Hampp, A. Geyer, The role of phosphopeptides in the mineralisation of silica, Organic & Biomolecular Chemistry, 2020, 18, 700 – 706.

 

2. Under review: 15.03.20: Marz, SA., Jan A. Kullmann, JA, Mattson S. O. Jones, MSO., Fecher-Trost, C., Eggert, S., Jung, M., Alexander, RT., & Friauf. E., Interactome of Glycine transporter 2: CAPS1 regulates GlyT2 activity by promoting endocytosis. J Biol Chem